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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HADHB
All Species:
31.21
Human Site:
Y244
Identified Species:
57.22
UniProt:
P55084
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55084
NP_000174.1
474
51294
Y244
S
R
L
E
Q
D
E
Y
A
L
R
S
H
S
L
Chimpanzee
Pan troglodytes
Q5R1W7
475
51377
Y245
S
R
L
E
Q
D
E
Y
A
L
R
S
H
S
L
Rhesus Macaque
Macaca mulatta
XP_001086547
482
52253
Y245
S
R
L
E
Q
D
E
Y
A
L
R
S
H
S
L
Dog
Lupus familis
XP_849696
475
51211
Y245
S
R
A
D
Q
D
E
Y
A
L
R
S
H
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99JY0
475
51368
Y245
S
R
M
E
Q
D
E
Y
A
L
R
S
H
S
L
Rat
Rattus norvegicus
Q60587
475
51396
Y245
S
R
M
E
Q
D
K
Y
A
L
R
S
H
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509364
555
59898
Y325
S
R
S
E
Q
D
E
Y
A
M
R
S
H
S
L
Chicken
Gallus gallus
XP_420004
474
50831
Y244
S
R
V
E
Q
D
E
Y
A
L
R
S
H
T
L
Frog
Xenopus laevis
NP_001080077
470
50522
H245
D
E
Y
A
L
R
S
H
T
L
A
K
K
A
Q
Zebra Danio
Brachydanio rerio
NP_956313
471
49953
A242
R
L
E
Q
D
E
F
A
L
R
S
H
T
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477378
469
50623
K243
L
R
S
H
T
L
A
K
E
A
Q
E
K
G
Y
Honey Bee
Apis mellifera
XP_624164
466
50900
A243
S
H
T
L
A
A
K
A
Q
Q
Q
G
Y
L
T
Nematode Worm
Caenorhab. elegans
P34255
448
47856
K229
T
L
A
S
E
A
A
K
N
G
K
F
T
D
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
95.2
94.3
N.A.
90.9
89.6
N.A.
75.8
83.9
82.9
78.4
N.A.
65.6
62.6
59
N.A.
Protein Similarity:
100
99.7
96.6
98.1
N.A.
96.8
97
N.A.
82.5
93.6
92.1
89.2
N.A.
79.7
78
74.2
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
93.3
86.6
N.A.
86.6
86.6
6.6
0
N.A.
6.6
6.6
0
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
93.3
100
20
13.3
N.A.
13.3
26.6
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
8
8
16
16
16
62
8
8
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
8
62
0
0
0
0
0
0
0
8
0
% D
% Glu:
0
8
8
54
8
8
54
0
8
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
0
8
0
8
0
% G
% His:
0
8
0
8
0
0
0
8
0
0
0
8
62
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
16
16
0
0
8
8
16
0
0
% K
% Leu:
8
16
24
8
8
8
0
0
8
62
0
0
0
16
62
% L
% Met:
0
0
16
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
62
0
0
0
8
8
16
0
0
0
8
% Q
% Arg:
8
70
0
0
0
8
0
0
0
8
62
0
0
0
0
% R
% Ser:
70
0
16
8
0
0
8
0
0
0
8
62
0
54
0
% S
% Thr:
8
0
8
0
8
0
0
0
8
0
0
0
16
8
8
% T
% Val:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
62
0
0
0
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _